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People return to their baseline weight and lose all cardiometabolic benefits in less than 2 years after stopping semaglutide or tirzepatide, a new meta-analysis found. “Real-world observations estimate that 50% of people
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Trajectory of the body weight after drug discontinuation in the treatment of anti-obesity medications | BMC Medicine
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Clinical Management of Weight Regain and Cardiometabolic Consequences After Discontinuation of GLP‐1 Receptor Agonists - Shah - 2026 - Diabetes, Obesity and Metabolism
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Suboptimal therapeutic responses associated with semaglutide in type 2 diabetes and obesity: A meta-analysis of randomized controlled trials: Cell Reports Medicine
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Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
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Weight gain after stopping GLP-1 drugs (by Patricia Toro, MD MPH)
22.30
