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In the SURMOUNT-4 trial, 82.5% of adults with obesity regained ≥25% of initial weight lost within one year of tirzepatide withdrawal; most showed reversal of cardiometabolic improvements. https://bit.ly/4rBMZgh
26.54
For the first time, tirzepatide and semaglutide were put in the same trial. SURMOUNT-5. Phase 3b RCT. 751 adults with obesity, no diabetes. 72 weeks. Both drugs at maximum tolerated dose. The
26.16
Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
28.23
SURMOUNT‐1 study design. This is a phase 3, multicenter, randomized,
20.94
Tirzepatide on ingestive behavior in adults with overweight or obesity: a randomized 6-week phase 1 trial
25.35
Tirzepatide Demonstrates 94% Diabetes Reduction, 22% Weight Loss in SURMOUNT -1 Study
21.77
Achieving BMI <25 kg/m2 was associated with reduced predicted risk of atherosclerotic cardiovascular disease in people with obesity or overweight on tirzepatide or placebo: a post hoc analysis of SURMOUNT-1, -3, and -
23.10
