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Loop diuretics like furosemide (Lasix) and bumetanide (Bumex) block the reabsorption of sodium, potassium, and chloride in the thick ascending limb of the loop of Henle. This interferes with concentrating the renal
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Furosemide (Lasix) 1. Class: Loop diuretic 2. Mechanism: Inhibition of the Na-K-Cl cotransporter in the thick ascending loop of Henle. This decreases the solute concentration in the renal medulla and limits the
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