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semaglutide side effects long term reddit Long Term GLP-1 Use: Maintenance and Offboarding

Marsoni M251S
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4.2 ★★★★★
Based on 1421 reviews
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Verified Purchase
B Helton
Houston, US
★★★★★ 1
PLEASE REVIEW — FORMULA CHANGED!!!
I wish I would’ve posted a review PRIOR to the formula changing but just know that I LOVED this serum. I’ve struggled with hormonal acne (PCOS) and eczema for as long as I can remember. Finally, last summer my dermatologist put me on (3) different RX including Spironolactone and Accutane. I was so tired so I stopped everything except for CeraVe cleanser, retinol (Tretinoin) and CeraVe healing ointment. My made up skin routine was working until I used too much Tretinoin and burned my face. I had read great reviews about this product so I thought, I might as well try it — and IT WORKED! I’ve been using this product for almost a year and I loved it. However, 3 weeks ago when I ordered it, I noticed the bottle had a green tint. I could tell after one use that the feel of the serum was different, more watery, not as thick as it used to be. The smell was also different. Still, I kept using it for nearly 2 weeks and I experienced 2 breakouts! Sure enough, I stopped the product and within a few days, my skin was back to normal. I am very upset because as someone who has extremely sensitive skin, this worked but unfortunately, the new formula isn’t for me.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 14, 2026
S
Verified Purchase
sandraday
Omaha, US
★★★★★ 5
Not greasy and no fragrance
Style: Updated Formula
Excellent moisturizer for my sensitive skin.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
A
Verified Purchase
Alice Cooper
Natrona Heights, US
★★★★★ 5
Great lotion for very dry skin
Style: Updated Formula
I had a laser done on my face and the products they gave me weren't working. This came highly recommended so I gave it a try. I'm very glad I did! It moisturized my face really well without appearing greasy. I used the rest when my face got dry from winter (in th midwest). Felt very rich and smooth. Medium thickness.
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Reviewed in the United States on December 19, 2025
K
Verified Purchase
Kcm228
Whiting, US
★★★★★ 5
Helps repair skin barrier
Style: Updated Formula
This stuff is amazing! It has drastically helped repair my skin barrier. I had a flare up of dermatitis right before an important event and this helped clear it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 21, 2026
K
Verified Purchase
KBL
Lowell, US
★★★★★ 5
Great Product
Style: Updated Formula
I will purchase this again. very gentle on the skin and moisturizes.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 14, 2026

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