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Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90-95% gets broken down safely by glucuronidation + sulfation → non-toxic stuff you pee out. *The problem
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The Metabolism of Acetaminophen and the Synthesis of Glutathione
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Problem 2: N-acetyl para-benzoquinone (NAPQI) is an oxidized
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Acetaminophen-induced Liver Injury: from Animal Models to Humans
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Acetaminophen – metabolism
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Clinical toxicity of Acetaminophen
22.23
NAPQI
21.74
