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Beyond GLP-1s: The Next Obesity Treatments
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Endoplasmic reticulum–mitochondria contact sites are signalling hubs connecting nutrient sensing and GLP-1 secretion in L cells of the mouse gut: from physiology to obesity and type 2 diabetes | Diabetologia
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GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction
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Dual GLP-1/GIP agonist tirzepatide modulates hepatic mitochondrial fusion–fission gene expression and oxidative stress in diabetic rats
27.40
Key Points From Episode: ⚡️ Metabolic disease may involve physical disruption of ER–mitochondria contact sites (mito-ERCS), not only “slow metabolism” in a vague sense. ⚡️ The paper frames mito-ERCS as a ~20
21.69
Polyphenols Ignite Metabolic Health via Mitochondria & GLP-1- Gut Bites MD
29.15
Schematic of ISD effect in parental and GLP-1 transfected MIN6 cells
24.19
