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Friday, May 29
Read this paper describing a large case series of patients with mast cell activation syndrome (MCAS) and comorbidities, whose MCAS associated symptoms improved significantly on GLP1 agonists. To summarize: 47 Read "Examining Glucagon Like Peptide 1 Receptor (GLP 1R) Agonists for Central Nervous System Disorders: Proceedings of a Workshop" at NAP.edu Current data suggest GLP 1 receptor agonists do not have direct deleterious effects on muscle beyond the lean mass loss typically seen with weight reduction. Observed declines in lean mass appear proportional to Nano Microneedle Patch Purosa Full article: Managing the gastrointestinal side effects of GLP 1 receptor agonists in obesity: recommendations for clinical practice
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Product Reviews
★★★★★ 3
Works good for my medium dog
Size: Large (5" x 3.25" x 9")
As expected. Good for medium chewers but not heavy chewers.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 6, 2026
★★★★★ 5
Wish I could give more stars after 8 months 🙌🏼
Size: Large (5" x 3.25" x 9")
I purchased this in June and I've come back in January to leave a review. This was the first toy I bought my dog I had it delivered while she was still in the shelter and it has lasted longer than any other toy. Not only can she not destroy it when she's actively trying but she still loves it she plays with it all the time I don't even need to put treats in it she just enjoys the texture. This toy was such a win. I have wasted so much money since then on other toys that say their indestructible and turn up in pieces. I wish I could give it more stars
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Reviewed in the United States on January 25, 2026
★★★★★ 5
Dog loves it! For tough chewers for sure
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Dog absolutely loves it, he’s super rough on all of his toys they usually last about 10 minutes bore they are torn to shreds. It’s lasting through his chewing so I’m happy. It’s also super cute.
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Reviewed in the United States on April 9, 2026
★★★★★ 5
Loch Yes
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Cute toy, dog really likes it. I had my doubts when I pulled it out, and honestly so did she, but the soft part bounces, so that got her going. We've had it for about a week. My dog is ~70 lbs and a moderate chewer, and this monster still gets regular play and is holding up well.
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Reviewed in the United States on April 18, 2026
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Great toys for aggressive chewers
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Reviewed in the United States on December 20, 2025
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