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Peptide Inhibitors Targeting FOXO4-p53 Interactions and Inducing Senescent Cancer Cell-specific Apoptosis
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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
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FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells
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A paper published in Cell investigated the effects of a FOXO4 peptide to target senescent cells in mice and reported improved kidney function and restoration of fur, suggesting that this could lead
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FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells
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Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment
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